20 Eylül 2012 Perşembe

Understanding The Mechanism of Changes in HIV to AIDS




Definition
Human Immunodeficiency Virus (HIV) is a disease that attacks the immune systemby invading CD4 + cells and lymphocytes.
 
Lymphocytes allows the immune system to function properly, and when finishedbecause of a virus attack, the immune system to be down capabilities.
 
 If the body has a number of CD4 + below 200, it is vulnerable to opportunisticinfections, which over time will develop into Acquired Immune DeficiencySyndrome (AIDS).
 
During the transition from HIV to AIDS, the HIV virus destroys white bloodcells. Viruses proliferate (replicate themselves) while weakening the immunesystem, and making the body vulnerable to infection.
Virus Replication and Cell Destruction
Host cell is active, then use the RNA polymerase (genetic material) to makecopies of HIV and messenger RNA (mRNA).
 
According to Joseph S. Cervio, MD, mRNA is used as a blueprint (blueprint)which makes the HIV protein chains in the body.
 
HIV protein chain is cut into smaller proteins which then collaborate with HIVRNA material to make more virus.
 
Virus escape from the host cell and attaches to an uninfected CD4 cells todestroy and replicate again.
In addition, routine inspection for cervical cancer is also important to do.
 
Mild symptoms of HIV can occur in 5 to 7 years after infection, and during thistime period the immune system becomes very weak.
 
Along with the increasing number of viruses, the number of CD4 + cells isdecreased, indicating late-stage HIV.
 
AIDS
When someone is diagnosed with AIDS because of the high number of viral and CD4+ cell count is low, the doctor will start therapy Highly Active AntiretroviralTherapy (HAART).
 
HAART is a strict regimen of medication is very powerful to reduce the additionof viral and increase levels of CD4.
 
When the number of CD4 + cell count falls below 200, the body will begin todevelop opportunistic infections, infections that normally would not occur inpeople with healthy immune systems.
A weakened immune system (weakeneddetrimentally) and can not fight the opportunistic infections 
characteristic ofAIDS virus.
 

Opportunistic infections (OI) is commonly include pneumocystis pneumonia (PCP),Kaposi's sarcoma, and cytomegalovirus.
 

Pneumocystis pneumonia is a lung infection that causes pneumonia. Kaposi'ssarcoma is a skin cancer that causes lesions, which are also known as an openwound (open sores).
 

Cytomegalovirus is an eye infection that can distort vision to produce blackspots or floaters, so it obscures the view.






Source : http://oketips.com/10382/

Hiç yorum yok:

Yorum Gönder